Atorvastatin or Lipitor 10 mg is used along with a proper diet to help lower “bad” cholesterol and fats (such as LDL, triglycerides) and raise “good” cholesterol (HDL) in the blood. It belongs to a group of drugs known as “statins.” It works by reducing the amount of cholesterol made by the liver.
Active liver disease (including unexplained persistent elevations in hepatic transaminase levels): Contraindicated
Concomitant lipid lowering therapy:
-Lipitor 10 mg may be used with bile acid resins; the combination of HMG-CoA reductase inhibitors (statins) and fibrates should be used with caution.
In patients taking cyclosporine or HIV protease inhibitors (tipranavir plus ritonavir) or the hepatitis C protease inhibitor (telaprevir):
-Avoid use with atorvastatin
In patients with HIV taking lopinavir plus ritonavir:
-Use with caution; lowest effective dose of atorvastatin should be used
Concomitant therapy with clarithromycin, itraconazole, or in patients with HIV taking a combination of saquinavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, or fosamprenavir plus ritonavir:
-Maximum dose: 20 mg/day; appropriate clinical assessment is recommended to ensure the lowest effective dose is employed
Concomitant therapy with the HIV protease inhibitor nelfinavir or the hepatitis C protease inhibitor boceprevir:
-Maximum dose: 40 mg/day; appropriate clinical assessment is recommended to ensure the lowest effective dose is employed
Safety and efficacy have not been established in pre-pubertal patients or patients younger than 10 years.